I received a contract from a publisher, but they do Ebooks and/or P.O.D. (publish on demand). I did a little research and they are a vanity press publisher. How damaging would it be if I were to publish my book through them, or should I wait for a big house to accept my book. I’ve been turned down by the largest (Simon Schuster) to the smallest. (Rose Cottage Press).
Personally I would not ever publish with a vanity press.
I would join a Writer's group and work on my book until a real publisher was interested.
It will only make it harder to get published if you go with a vanity press.